描述
I 型胶原酶从溶组织梭菌制备，用于细胞和组织的解离。
I 型胶原酶可应用于如下组织制备细胞：
• 上皮组织
• 肺
• 脂肪
• 肾上腺组织
胶原酶是一种蛋白酶，它能够特异性的结合 Pro-X-Glyc-Pro序列中，中性氨基酸（X）和甘氨酸之间的肽键。该序列高频率的存在于胶原中。胶原酶是唯一的一种可以降解广泛存在于结缔组织中的具有三股螺旋的天然胶原纤维的蛋白酶。
Life Technologies 大家庭中的细胞培养产品。
Life Technologies公司已准备就绪，以满足您的细胞培养需要一个全面的选择，包括培养基，营养添加剂，盐溶液，缓冲液，化学物质，解离试剂和转染的试剂。您可以依靠严格的质量控制和技术支持，以保证您的满意。仅供研究使用。 不用于任何动物或人类治疗或诊断使用。
原厂资料：
Collagenase is a protease that cleaves the bond between a neutral amino acid (X) and glycine in the sequence Pro-X-Gly-Pro, which is found with high frequency in collagen. Collagenase is unique among proteases in its ability to degrade the triple-helical native collagen fibrils commonly found in connective tissues such as skin, tendon, blood vessels, and bone. Collagenase disaggregation is suitable for the culture of human tumors, mouse kidney, human adult and fetal brain, and many other tissues including epithelium. Collagenase is relatively gentle, dissociates well at physiological temperature and pH, and requires no mechanical agitation or special equipment.
Gibco® Collagenase Type I is isolated from Clostridium histolyticum and packaged as a lyophilized, non-sterile powder for research use in cell or tissue dissociation, and organ perfusions. Gibco® Collagenase Type I activity is guaranteed to be greater than 125 units/mg. Compared to other collagenase preparations, Gibco® Collagenase Type I has average levels of collagenase, caseinase, clostripain, and tryptic activities, and is well-suited for the digestion of fat, adrenal, and liver cells or tissues.